Your cow herd depends on pregnancies. Your pocket book depends on live calves. Manage health and reproduction in your cow herd to maximize pregnancies and calf health.

There are a lot of components to pre-breeding vaccinations. A general outline of viruses important to respiratory and reproductive health are outlined below. Ensure that the following are included in your pre-breeding vaccines.
1. Bovine Viral Diarrhea Virus, also known as BVD or BVDV can affect the respiratory, reproductive, and gastrointestinal systems of cattle. In cows, infection with this virus during the first 150 days of pregnancy can result in a persistently infected (PI) calf. The immune system of a BVD-PI calf recognizes the BVD virus as self, which results in the calf replicating and shedding this virus throughout its lifetime. The PI calf sheds virus particles in respiratory secretions, causing respiratory disease in neighboring calves. In addition, PI calves that are exposed to cytopathic strains of BVD can develop mucosal disease, which affects the digestive tract and commonly results in death of the calf.
2. Infectious Bovine Rhinotracheitis, or IBR, a highly contagious respiratory infection, can also cause infertility or abortion in cows. When using a modified-live vaccine, the IBR component can cause inflammation around the ovary and can either lead to reduced pregnancy rates in the first cycle following vaccination, or abortion in pregnant cattle.
3. Parainfluenza 3, also known as PI3, is a virus that primarily causes respiratory disease and is especially problematic when combined with BVD or IBR, often leading to secondary bacterial infections and contributing to bovine respiratory disease complex (BRD).
4. Respiratory Syncytial Virus or BRSV is another viral component that primarily causes respiratory disease in calves and contributes to bovine respiratory disease complex (BRD).
Modified live vaccines create a better, longer lasting immunity against viruses and are protective against development of PI calves. Modified-live vaccinations must be given at least 30 days prior to breeding, with two doses required during the first year of use. Vaccination of pregnant females or calves nursing cows that have not been vaccinated with a MLV within the last 12 months can result in abortion.
Killed Vaccines, on the other hand, are safe for use in cows during all stages of pregnancy, making them preferred in herds with longer breeding and calving seasons.
Vibriosis is caused by the bacteria Campylobacter fetus, which is spread venerally by asymptomatic bulls. Infection causes reduced pregnancy rates by preventing embryo implantation or causing early pregnancy loss.
Leptospirosis is a bacteria with many different serotypes, with Leptospira borgpetersenii serovar Hardjo type hardjo-bovis being one of the most significant causes of Leptospirosis infections in the US. Most vaccines contain 5 strains of Leptospirosis. Leptospirosis is spread through the urine of infected animals, which infects cows through the mucosa in the mouth and nose leading to infertility and abortion in cattle. It is generally recommended to booster vaccinations including leptospirosis when cows are in the second period of pregnancy.
Leptospirosis is a zoonotic disease, so care should be taken if handling aborted fetuses. Abortion in herds can occur in 1-2% of animals normally, but should be investigated at a higher rate or if multiple cows abort in a short time period.
Modified live vaccination should be given at least 30 days prior to breeding.
Pinkeye
7-way Clostridial
Multi-Min
Killed or intranasal
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Deworm
Growth Implant
Pinkeye Vaccination
30-90 days
60-90 days
Recheck any open cows that might have been short bred at the time of initial ultrasound
Calves should receive two rounds of vaccinations around the time of weaning
One round of vaccinations should include vaccination for Manhiemia Haemolytica
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